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Editor’s Choice

Editor's Choice

How viruses and bacteria balance each other in the gut microbiome

July 22, 2020 Microbiome Times

The adage “all things in moderation” applies not to just to food and drink, but also to the legions of bacteria inside our guts helping us digest that food and drink. It turns out the […]

Editor's Choice

Modelling Biology Using Graph Language

May 12, 2020 Sven Sewitz and Radouane Oudhriri

Abstract: At Eagle Genomics, we use graph databases to model the biological domain. This enables the scientist to access the relevant information and insight they are looking for in a number of industries, including pharmaceuticals, healthcare […]

Editor's Choice

Compositional Data Analysis Approaches to Improve Microbiome Studies – From Collection to Conclusions

May 12, 2020 Jean M Macklaim

Abstract: As vast amounts of high-throughput data are generated from sequencing the microbiome, suitable analysis approaches are needed to effectively evaluate the data and reach robust conclusions to power studies incorporating microbiome research questions. Sequencing […]

Editor's Choice

New Statistical Method Identifies Cytokines that Distinguish Stool Microbiomes

May 12, 2020 Bill Shannon

Abstract: A wide class of formal statistical methods exist that can be developed and applied to microbiome data. In this talk we present a statistical regression model. Regressing an outcome or dependent variable onto a set […]

Editor's Choice

Rebiotix and Ferring announce world’s first with positive preliminary pivotal Phase 3 data for investigational microbiome-based therapy

May 6, 2020 Microbiome Times

Today, Rebiotix and Ferring Pharmaceuticals announced positive preliminary findings from their ongoing pivotal Phase 3 trial of the investigational microbiome-based treatment, RBX2660. These preliminary positive efficacy findings mark an important milestone, advancing RBX2660 in its […]

Editor's Choice

Microbiome after coronavirus: Investing in the power of microbes

April 30, 2020 Luis Gosálbez

The COVID-19 crisis is causing immense suffering and an appalling death toll. It has also dramatically impacted our personal and professional lives, and individuals, businesses and investors can’t wait to get back to normalcy. However, […]

Editor's Choice

Until next Probiota, savor the learnings of Probiota Dublin 2020

April 30, 2020 Nina Vinot

Probiota is set with the ambition to connect business and science of the microbiome space, build community, start conversations and inspire innovation, as very well expressed by Nathan Gray from William Reed. Probiota this year […]

Editor's Choice

Validity Attack on US Patent for Bifidobacetrium Combo-Therapy: What can we learn?

April 29, 2020 Craig Thomson, Dr Leena Contarino, Dr Lauris Kemp, David Resnick and Mark FitzGerald

Although the April 15, 2020 decision of the U.S. Patent Trial and Appeal Board (PTAB) was to invalidate The University of Chicago’s US microbiome patent, much can be learned and some positive notes echo from […]

Editor's Choice

The Lactobacillus taxonomy change has arrived! What do you need to know?

April 21, 2020 Nina Vinot and Marco Pane

Taxonomy is the branch of science that classifies and names organisms. Lactobacillus were first described in 1901 with Lactobacillus delbrueckii, a species indispensable in yogurt, and grew exponentially since the beginning of the 21stcentury thanks to […]

Editor's Choice

A common gut microbe secretes a carcinogen

April 4, 2020 Microbiome Times

Cancer mutations can be caused by common gut bacteria carried by many people. This was demonstrated by researchers from the Hubrecht Institute (KNAW) and Princess Máxima Center in Utrecht, the Netherlands. By exposing cultured human […]

Editor's Choice

The Microbiome Biotech Landscape: An Analysis of the Pharmaceutical Pipeline

March 26, 2020 Luis Gosálbez

Introduction The microbiome is one of the hottest areas in biotechnology, as countless studies have linked its composition and activity with human disease1,2, especially in illnesses of poorly understood mechanisms, with high medical unmet needs. […]

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