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Editor’s Choice

Editor's Choice

Until next Probiota, savor the learnings of Probiota Dublin 2020

April 30, 2020 Nina Vinot

Probiota is set with the ambition to connect business and science of the microbiome space, build community, start conversations and inspire innovation, as very well expressed by Nathan Gray from William Reed. Probiota this year […]

Editor's Choice

Validity Attack on US Patent for Bifidobacetrium Combo-Therapy: What can we learn?

April 29, 2020 Craig Thomson, Dr Leena Contarino, Dr Lauris Kemp, David Resnick and Mark FitzGerald

Although the April 15, 2020 decision of the U.S. Patent Trial and Appeal Board (PTAB) was to invalidate The University of Chicago’s US microbiome patent, much can be learned and some positive notes echo from […]

Editor's Choice

The Lactobacillus taxonomy change has arrived! What do you need to know?

April 21, 2020 Nina Vinot and Marco Pane

Taxonomy is the branch of science that classifies and names organisms. Lactobacillus were first described in 1901 with Lactobacillus delbrueckii, a species indispensable in yogurt, and grew exponentially since the beginning of the 21stcentury thanks to […]

Editor's Choice

A common gut microbe secretes a carcinogen

April 4, 2020 Microbiome Times

Cancer mutations can be caused by common gut bacteria carried by many people. This was demonstrated by researchers from the Hubrecht Institute (KNAW) and Princess Máxima Center in Utrecht, the Netherlands. By exposing cultured human […]

Editor's Choice

The Microbiome Biotech Landscape: An Analysis of the Pharmaceutical Pipeline

March 26, 2020 Luis Gosálbez

Introduction The microbiome is one of the hottest areas in biotechnology, as countless studies have linked its composition and activity with human disease1,2, especially in illnesses of poorly understood mechanisms, with high medical unmet needs. […]

Editor's Choice

FDA Safety Alert Regarding Use of Fecal Microbiota for Transplantation and Risk of Serious Adverse Events Likely Due to Transmission of Pathogenic Organisms

March 13, 2020 Microbiome Times

The Food and Drug Administration (FDA) is informing health care providers and patients of the potential risk of serious or life-threatening infections with the use of fecal microbiota for transplantation (FMT). The agency is now aware […]

Editor's Choice

Securing Commercial Advantage through Innovations in Microbiome Therapeutic Production

March 4, 2020 Craig Thomson and Dr Leena Contarino

Introduction With every article of the Microbiome Times, one sees the therapeutic microbiome industry edging ever-closer to full commercialisation of their products. Understandably, much of the focus has been on the challenging process of demonstrating […]

Editor's Choice

Dr. Georg Gerber on the computational approaches that will enable new microbiome diagnostics and therapeutics

February 12, 2020 Kristina Campbell

Many different chronic diseases have been associated with distinct gut microbiome ‘signatures’, but what has proved challenging to date is the translation of the compositional and functional microbiome differences into novel diagnostics and therapeutics. Moving […]

Editor's Choice

Non-living microbiome therapeutics: European organisation strives to bring regulatory challenges for these drug products into focus

February 3, 2020 Kristina Campbell

The human microbiome is often described as an ‘ecosystem’, evoking a complex collection of organisms that are alive and dynamic. So when considering strategies for modulating the human microbiome to prevent or treat a disease, […]

Editor's Choice

5-minute Microbiome Science Roundup: December 2019

January 23, 2020 Kristina Campbell

First, it was a bank teller who mentioned to me she’d learned about the skin microbiome from a Dove commercial. Then it was a woman whose drink I’d accidentally touched at the Starbucks counter, who […]

Editor's Choice

Decoding the microbiome for clinical success – Can we increase cancer immunotherapy response rate by exploring metagenomes?

January 23, 2020 Kaja Milanowska-Zabel, Ph.D. and Sonia Wróbel

The overlap between the gut microbiome and tumor progression, metastasis and treatment sensitivity is one of the fastest growing areas of cancer research1. Recent studies have demonstrated that the microbiome plays important roles in oncogenesis […]

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