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Month: May 2020

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A Checklist for Moving an LBP Through Manufacturing: The Biotech – CDMO Relationship

May 29, 2020 Kristina Campbell

With increasing evidence for microbial involvement in many human diseases, live biotherapeutic products (LBPs)—living microbes administered therapeutically—have emerged as a group of exciting new drug candidates. Although the LBP regulatory environment remains uncertain, companies all […]

Pharma & Human Health

Viruses from poo can help combat obesity and diabetes

May 18, 2020 Staff Editor

Obese mice with unhealthy lifestyles gain significantly less weight and avoid type 2 diabetes when they receive viruses transplanted from the stool of lean mice. These are the findings of a new University of Copenhagen […]

Editor's Choice

Modelling Biology Using Graph Language

May 12, 2020 Sven Sewitz and Radouane Oudhriri

Abstract: At Eagle Genomics, we use graph databases to model the biological domain. This enables the scientist to access the relevant information and insight they are looking for in a number of industries, including pharmaceuticals, healthcare […]

Editor's Choice

Compositional Data Analysis Approaches to Improve Microbiome Studies – From Collection to Conclusions

May 12, 2020 Jean M Macklaim

Abstract: As vast amounts of high-throughput data are generated from sequencing the microbiome, suitable analysis approaches are needed to effectively evaluate the data and reach robust conclusions to power studies incorporating microbiome research questions. Sequencing […]

Editor's Choice

New Statistical Method Identifies Cytokines that Distinguish Stool Microbiomes

May 12, 2020 Bill Shannon

Abstract: A wide class of formal statistical methods exist that can be developed and applied to microbiome data. In this talk we present a statistical regression model. Regressing an outcome or dependent variable onto a set […]

Finance

Intralytix Receives Multimillion-Dollar Clinical Trial Award From NIAID to Manage Shigella Infections in Humans

May 11, 2020 Staff Editor

Intralytix, Inc. announced that it has received a multimillion-dollar grant (AI 148054) from the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), for the clinical development of its bacteriophage therapy […]

Editor's Choice

Rebiotix and Ferring announce world’s first with positive preliminary pivotal Phase 3 data for investigational microbiome-based therapy

May 6, 2020 Staff Editor

Today, Rebiotix and Ferring Pharmaceuticals announced positive preliminary findings from their ongoing pivotal Phase 3 trial of the investigational microbiome-based treatment, RBX2660. These preliminary positive efficacy findings mark an important milestone, advancing RBX2660 in its […]

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The Microbiome Drug Database

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The Microbiome Drug Landscape report: Promising clinical performance and signs of a maturing industry

Market Reports
October 26, 2020
Abstract Year 2020 has been a pivotal year for microbiome-focused drug companies. This year the industry saw the release of two much-anticipated Phase 3 studies, which showed positive results and set the stage for new [...]

Editor’s Choice

  • Kaleido Biosciences Announces Positive Interim Results of Controlled Study of KB109 in Patients with Mild-to-Moderate COVID-19
    January 20, 2021
  • Poor gut health connected to severe COVID-19, new review shows
    January 18, 2021
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